Prognosis value of residual disease monitoring by polymerase chain reaction in patients with CBF beta/MYH11-positive acute myeloblastic leukemia.
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چکیده
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منابع مشابه
Incidence and prognostic importance of molecular genetic defects in children with acute myeloblastic leukemia.
INTRODUCTION Acute myeloblastic leukemia (AML) accounts for 15 to 25 percent of childhood acute leukemias. The most common genetic abnormalities seen in pediatric AML patients are AML1-ETO, PML-RARα and CBFB-MYH11 genes resulting in t(8;21), t(15;17) and inv(16). These genetic defects are seen in approximately 20-25% of AML patients. OBJECTIVE We investigated in this study, incidence and prog...
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ورودعنوان ژورنال:
- Blood
دوره 89 6 شماره
صفحات -
تاریخ انتشار 1997